Transmutation

The fool of the tarot, standing over the open jaws of the crocodile. The fight against the three traitors.
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In the Master’s words
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What the card shows
In the upper part we find the Black Moon and the White Moon; the antitheses. In the middle section, a magician with the Staff of the Patriarchs in one hand and the Ansate or Tao Cross in the other hand. He is found standing upon a crocodile which waits with open jaws to devour him.
— Samael Aun Weor, Tarot and Kabbalah, ch. 21
Its esoteric meaning
Arcanum number 21 has been confused with Arcanum number 22 which is the Crown of life. Arcanum number 21 is the “Madman of the Tarot”, or the “Transmutation”. The kabalistic addition gives us 2 + 1 = 3. In this Arcanum 21 the Initiate has to fight against the “3” Traitors of Hiram Abiff: the demon of Desire, the demon of the Mind and the demon of Ill-will. One is never in more danger of being a demon than when one is closest to being an angel.
— Samael Aun Weor, Tarot and Kabbalah, ch. 21
His synthesis
Transmutation: The Fool, Foolishness “Total Demoralisation due to evil. The Magic Key, Rune Olin. The Antithesis; enemies of Hiram Abiff.”
— Samael Aun Weor, Tarot and Kabbalah, ch. 86, Prediction and synthesis